Abnormal mitosis

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Abnormal mitosis

Mitosis. Fluorescence micrograph of a cell during abnormal anaphase of mitosis (nuclear division). During mitosis two daughter nuclei are formed from one parent nucleus. This requires organisation of the chromosomes (blue) and mitotic spindles (red) to ensure that each cell retains an exact copy of the parent cells genetic information. Usually at anaphase the two identical sister chromatids that make up a chromosome are pulled to opposite ends of the cell. However, in this cell the spindles are having trouble separating the chromatids. Abnormal mitosis can lead to cell abnormalities or cell death

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6454281

© DR PAUL ANDREWS, UNIVERSITY OF DUNDEE/ SCIENCE PHOTO LIBRARY

Anaphase Bipolar Centromere Centromeres Chromatid Chromatids Chromosome Chromosomes Cytological Cytology Cytoskeletal Cytoskeleton Dividing Division Enzyme Fixed Fluorescence Micrograph Fluorescent Hela Cell Microscope Microtubule Microtubules Mitosis Mitotic Nuclear Poles Segregating Segregation Separating Spindle Spindles Stained Structures Wide Field Deconvoluted Abnormal Deoxyribonucleic Acid Genetics

EDITORS COMMENTS
This print captures the intricate process of mitosis, specifically an abnormal anaphase. Mitosis is a crucial stage in cell division where one parent nucleus gives rise to two daughter nuclei, ensuring the preservation of genetic information. The image showcases the organization of chromosomes (blue) and mitotic spindles (red), which play a pivotal role in maintaining the fidelity of DNA replication. In this particular cell, we witness a deviation from the norm as the spindles encounter difficulty in separating sister chromatids. This aberrant mitosis can have severe consequences such as cellular abnormalities or even cell death. The significance lies in understanding how errors during mitosis can impact overall cellular health and function. The fluorescence micrograph provides us with a detailed view into this biological phenomenon by utilizing staining techniques to highlight specific structures within the cell. We observe single cells undergoing division under intense microscopic scrutiny, revealing their cytoskeletal components and enzymatic activity. By studying these processes at a molecular level, scientists gain insights into various aspects of genetics and cellular biology. This wide field deconvoluted image serves as both an educational tool for aspiring biologists and a testament to the complexity inherent in every living organism's existence.

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