Actin-based motility, SEM C017 / 8334

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Actin-based motility, SEM C017 / 8334

Actin-based motility. Coloured scanning electron micrograph (SEM) of Shigella sp. bacteria (pink) infecting cells. Filaments of the protein actin, which is part of the cells cystoskeleton, have been stained green. The bacteria use the actin to help them infect other cells. They initiate the growth of actin filaments that push them against the cell membrane. This causes the cell membrane to grow outwards and allows the bacteria to infect other cells without passing into the extracellular space. Shigella sp. are Gram-negative rod-shaped bacteria. They infect the large intestine, causing dysentery, which can vary in severity from a mild attack of diarrhoea to an acute infection

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Media ID 9211639

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Bacilli Bacillus Bacteria Bacterial Bacteriology Bacterium Cytoskeleton Gram Negative Infecting Infection Intracellular Microbiology Motile Motility Optical Spreading Actin Filaments Microbiological Pathogen Protein

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This print from Science Photo Library showcases the fascinating world of actin-based motility. In this coloured scanning electron micrograph (SEM), we witness the intricate dance between Shigella sp. bacteria and host cells. The pink-hued Shigella sp. bacteria take center stage, infecting cells with their cunning tactics. The green-stained filaments of actin, a crucial protein in the cell's cytoskeleton, are beautifully highlighted against the backdrop. These filaments play a pivotal role in aiding the bacteria's invasion strategy. Using actin as their secret weapon, these Gram-negative rod-shaped bacteria initiate the growth of actin filaments that exert pressure on the cell membrane. As a result, the membrane extends outward, providing an entry point for infection without traversing into extracellular space. Shigella sp. , notorious for causing dysentery ranging from mild to severe forms, demonstrate their motile nature through this image. Their ability to manipulate actin enables them to propel themselves against cellular barriers and spread throughout their environment. Through this SEM snapshot, we gain insight into both bacterial pathogenesis and cellular biology at its finest. It serves as a reminder of how microscopic organisms can wield immense power within our bodies while simultaneously showcasing the beauty hidden within scientific exploration.

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