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Actin-based motility, light micrograph C017 / 8333
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Actin-based motility, light micrograph C017 / 8333
Actin-based motility. 3D model made from optical sections of Shigella sp. bacteria (pink) infecting cells. Filaments of the protein actin, which is part of the cells cystoskeleton, have been stained green. The bacteria use the actin to help them infect other cells. They initiate the growth of actin filaments that push them against the cell membrane. This causes the cell membrane to grow outwards and allows the bacteria to infect other cells without passing into the extracellular space. Shigella sp. are Gram-negative rod-shaped bacteria. They infect the large intestine, causing dysentery, which can vary in severity from a mild attack of diarrhoea to an acute infection
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Media ID 9211597
© SCIENCE PHOTO LIBRARY
Bacilli Bacillus Bacteria Bacterial Bacteriology Bacterium Cytoskeleton Fluorescence Micrograph Gram Negative Infecting Infection Intracellular Microbiology Motile Motility Optical Spreading Three Dimensional Actin Filaments Light Micrograph Light Microscope Microbiological Pathogen Protein
EDITORS COMMENTS
This print showcases the fascinating world of actin-based motility in Shigella sp. bacteria. The image, captured using a light microscope and transformed into a stunning 3D model, reveals the intricate relationship between these pathogenic bacteria and their host cells. In this mesmerizing composition, the Shigella sp. bacteria (depicted in pink) can be seen infecting cells by utilizing actin filaments stained green. Actin is an essential component of the cell's cytoskeleton, but these clever bacteria have found a way to exploit it for their own benefit. By initiating the growth of actin filaments, the bacteria push themselves against the cell membrane, causing it to protrude outwards. This unique mechanism allows them to infect neighboring cells without ever leaving the intracellular space or entering extracellular areas. Shigella sp. , gram-negative rod-shaped bacteria notorious for causing dysentery in humans, are brought to life through this vivid portrayal. Their motile nature and ability to manipulate actin make them formidable pathogens capable of varying degrees of infection severity. Through this extraordinary print from Science Photo Library, we gain insight into the complex interplay between biology and infection spreading at a microscopic level. It serves as a reminder that even within seemingly invisible realms lies an astonishing world waiting to be explored by scientists and researchers alike.
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