Enzyme catalysing DNA recombination F006 / 9395
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Enzyme catalysing DNA recombination F006 / 9395
Enzyme catalysing DNA recombination. Molecular model of the enzyme CRE (cyclization recombination) recombinase (green and purple) mediating the recombination of strands of DNA (deoxyribonucleic acid, red and blue) at a Holliday Junction. This recombination is a natural genetic process known as crossing over, and involves the mixing of two strands of DNA. Recombinase enzymes snip open each DNA strand, starting the process going and forming a four-way alignment known as a Holliday Junction. It is this structure that other recombinases, like CRE, attach to as they continue the process
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9254511
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Alpha Helix Beta Sheet Cre Recombinase Crossing Over Crossover Cyclization Recombination Enzyme Genetic Diversity Holliday Junction Homologous Chromosomes Homologous Recombination Mediating Nucleic Acid Proteomics Recombination Recombining Strand Tertiary Structure Biochemical Biochemistry Cutouts Deoxyribonucleic Acid Genetics Molecular Molecular Model Molecular Structure Protein
EDITORS COMMENTS
This print showcases the intricate process of enzyme catalysing DNA recombination. In this molecular model, we observe the enzyme CRE (cyclization recombination) recombinase in green and purple, mediating the recombination of strands of DNA depicted in red and blue at a Holliday Junction. This natural genetic phenomenon known as crossing over involves the mixing of two strands of DNA. Recombinase enzymes play a crucial role by snipping open each DNA strand, initiating the process and forming a four-way alignment called a Holliday Junction. It is at this structure that other recombinases like CRE attach themselves to continue the recombination process. The white background enhances our focus on this remarkable illustration which holds immense significance in biology, research, medicine, and genetics. The molecular structure reveals alpha helixes and beta sheets within the protein while highlighting nucleic acids' tertiary structure. Understanding these mechanisms contributes to our knowledge of genetic diversity and proteomics. Homologous recombination between homologous chromosomes is vital for maintaining genomic stability during cell division. This artwork serves as an invaluable tool for healthcare professionals involved in biochemistry or studying medical illustrations related to DNA processes. With its cutout design, it provides clarity on complex concepts such as crossover events occurring at Holliday Junctions. Overall, LAGUNA DESIGN/SCIENCE PHOTO LIBRARY has beautifully captured an essential aspect of molecular biology through this visually striking image.
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