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Alpha Helix Collection

The alpha helix, a fundamental structure in biology, plays a crucial role in various molecular processes

Background imageAlpha Helix Collection: DNA transcription, molecular model

DNA transcription, molecular model. Secondary structure of the enzyme RNA polymerase II synthesising a mRNA (messenger ribonucleic acid, lilac) strand from a DNA (deoxyribonucleic acid)

Background imageAlpha Helix Collection: Secondary structure of proteins, artwork

Secondary structure of proteins, artwork
Secondary structure of proteins, computer artwork. The secondary structure is the shape taken by the strands of proteins, which are biological polymers of amino acids

Background imageAlpha Helix Collection: Nucleosome molecule

Nucleosome molecule, computer model. A nucleosome is a subunit of chromatin, the substance that forms chromosomes. It consists of a short length of DNA (deoxyribonucleic acid)

Background imageAlpha Helix Collection: Bacterial ribosome

Bacterial ribosome. Computer model showing the secondary structure of a 30S (small) ribosomal sub-unit from the bacteria Thermus thermophilus

Background imageAlpha Helix Collection: HIV reverse transcription enzyme

HIV reverse transcription enzyme. Molecular models of the reverse transcriptase enzyme found in HIV (the human immunodeficiency virus)

Background imageAlpha Helix Collection: Hepatitis C virus enzyme, molecular model

Hepatitis C virus enzyme, molecular model
Hepatitis C virus enzyme. Molecular model of a genetic enzyme from the Hepatitis C virus. This enzyme is called HC-J4 RNA polymerase

Background imageAlpha Helix Collection: Manganese superoxide dismutase enzyme F006 / 9423

Manganese superoxide dismutase enzyme F006 / 9423
Manganese superoxide dismutase enzyme, molecular model. This enzyme scavenges and decomposes the potentially toxic first reduction product, superoxide, of aerobic respiration

Background imageAlpha Helix Collection: Argonaute protein molecule F006 / 9526

Argonaute protein molecule F006 / 9526
Argonaute protein, molecular model. This protein forms the RNA-induced silencing complex (RISC) along with a small interfering RNA (ribonucleic acid) molecule

Background imageAlpha Helix Collection: Argonaute protein and microRNA F006 / 9752

Argonaute protein and microRNA F006 / 9752
Argonaute protein. Molecular model of human argonaute-2 protein complexed with microRNA (micro ribonucleic acid). This protein is part of the RNA-induced silencing complex (RISC)

Background imageAlpha Helix Collection: Immunoglobulin G antibody and egg white F006 / 9682

Immunoglobulin G antibody and egg white F006 / 9682
Immunoglobulin G and egg white. Molecular model of an immunoglobulin G (IgG) antibody bound to a molecule of egg white. This is the most abundant immunoglobulin and is found in all body fluids

Background imageAlpha Helix Collection: Cytochrome P450 complex F006 / 9669

Cytochrome P450 complex F006 / 9669
Cytochrome P450 complex. Molecular model of a complex composed of cytochrome P450, carbon monoxide and camphor. Cytochrome molecules perform oxidation and reduction reactions for electron transport

Background imageAlpha Helix Collection: Succinyl-CoA synthetase enzyme F006 / 9592

Succinyl-CoA synthetase enzyme F006 / 9592
Succinyl-CoA synthetase bound to GTP, molecular model. Also known as succinyl coenzyme A synthetase (SCS), this enzyme catalyses the reversible reaction between succinyl-CoA and succinic acid

Background imageAlpha Helix Collection: RNA-induced silencing complex F006 / 9586

RNA-induced silencing complex F006 / 9586
RNA-induced silencing complex (RISC), molecular model. This complex consists of a bacterial argonaute protein (top) bound to a small interfering RNA (siRNA) molecule (red and blue)

Background imageAlpha Helix Collection: Foot-and-mouth disease virus F006 / 9556

Foot-and-mouth disease virus F006 / 9556
Foot-and-mouth disease virus. Molecular model of the foot-and-mouth disease (FMD) virus (Aphtae epizooticae) protein coat (capsid)

Background imageAlpha Helix Collection: Adenovirus penton base protein F006 / 9542

Adenovirus penton base protein F006 / 9542
Adenovirus penton base protein, molecular model. This protein molecule is a subunit called a penton, forming the vertices of the capsid of this adenovirus

Background imageAlpha Helix Collection: Rhinovirus 16 capsid, molecular model F006 / 9431

Rhinovirus 16 capsid, molecular model F006 / 9431
Rhinovirus 16 capsid, molecular model. This is human rhinovirus 16. The rhinovirus infects the upper respiratory tract and is the cause of the common cold. It is spread by coughs and sneezes

Background imageAlpha Helix Collection: Citrate acid cycle enzyme F006 / 9305

Citrate acid cycle enzyme F006 / 9305
Citrate acid cycle enzyme. Molecular model of the enzyme dihydrolipoamide succinyltransferase. This enzyme is involved in the citric acid (or Krebs) cycle

Background imageAlpha Helix Collection: Parathyroid hormone molecule

Parathyroid hormone molecule. Computer model showing the structure of parathyroid hormone (PTH), or parathormone. Atoms are colour-coded (carbon: dark grey, hydrogen: light grey, oxygen: red)

Background imageAlpha Helix Collection: Haemagglutinin viral surface protein F007 / 9932

Haemagglutinin viral surface protein F007 / 9932
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

Background imageAlpha Helix Collection: Haemagglutinin viral surface protein F007 / 9931

Haemagglutinin viral surface protein F007 / 9931
Haemagglutinin viral surface protein. Molecular model of haemagglutinin, a surface protein from the influenza virus, complexed with a neutralising antibody

Background imageAlpha Helix Collection: Rubisco enzyme molecule F006 / 9776

Rubisco enzyme molecule F006 / 9776
Rubisco. Molecular model of the enzyme rubisco (ribulose bisphosphate carboxylase oxygenase) complexed with 2-carboxyarabinitol biphosphate

Background imageAlpha Helix Collection: Rubisco enzyme molecule F006 / 9779

Rubisco enzyme molecule F006 / 9779
Rubisco. Molecular model of the enzyme rubisco (ribulose bisphosphate carboxylase oxygenase) complexed with ribulose-1, 5-biphosphate

Background imageAlpha Helix Collection: NADP-dependent isocitrate dehydrogenase F006 / 9778

NADP-dependent isocitrate dehydrogenase F006 / 9778
NADP-dependent isocitrate dehydrogenase, molecular model. This enzyme catalyses the third step in the citric acid (or Krebs) cycle, the process by which mitochondria convert glucose to energy

Background imageAlpha Helix Collection: Catalase, molecular model F006 / 9774

Catalase, molecular model F006 / 9774
Catalase. Molecular model of catalase from a cow liver. This enzyme to water and oxygen. Hydrogen peroxide is a highly toxic byproduct of a number of normal cellular processes

Background imageAlpha Helix Collection: Glycogen phosphorylase molecule F006 / 9775

Glycogen phosphorylase molecule F006 / 9775
Glycogen phosphorylase. Molecular model of glycogen phosphorylase bound to AMP (adenosine monophosphate). This is an enzyme involved in breaking down glycogen

Background imageAlpha Helix Collection: Triose phosphate isomerase molecule F006 / 9777

Triose phosphate isomerase molecule F006 / 9777
Triose phosphate isomerase (TPI), molecular model. TPI is essential for glycolysis and catalyses the reversible interconversion of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate

Background imageAlpha Helix Collection: Bacterial alpha-hemolysin toxin F006 / 9771

Bacterial alpha-hemolysin toxin F006 / 9771
Bacterial alpha-hemolysin toxin, molecular model. This toxin is secreted by the bacterium Staphylococcus aureus. It is an example of a pore-forming toxin

Background imageAlpha Helix Collection: Metabolic enzyme molecule F006 / 9770

Metabolic enzyme molecule F006 / 9770
Metabolic enzyme. Molecular model of the enzyme aconitase with isocitrate bound. Aconitase is involved in the citric acid (or Krebs) cycle

Background imageAlpha Helix Collection: Dihydrofolate reductase molecule F006 / 9772

Dihydrofolate reductase molecule F006 / 9772
Dihydrofolate reductase, molecular model. This enzyme converts the vitamin folic acid into a coenzyme

Background imageAlpha Helix Collection: HIV-1 protease and inhibitor F006 / 9773

HIV-1 protease and inhibitor F006 / 9773
HIV-1 protease and inhibitor. Molecular model of the enzyme HIV-1 protease (pink and blue ribbons) bound to an inhibitor molecule (centre)

Background imageAlpha Helix Collection: Ribonuclease A molecule F006 / 9768

Ribonuclease A molecule F006 / 9768
Ribonuclease A (RNAse A), molecular model. Ribonuclease (RNase) is a type of nuclease that catalyses the degradation of RNA (ribonucleic acid)

Background imageAlpha Helix Collection: Pepsin stomach enzyme F006 / 9767

Pepsin stomach enzyme F006 / 9767
Pepsin stomach enzyme, molecular model. Pepsin is a protease enzyme that is secreted as part of gastric juice into the stomach in an inactive form known as pepsinogen

Background imageAlpha Helix Collection: Flock house virus capsid F006 / 9755

Flock house virus capsid F006 / 9755
Flock house virus capsid, molecular model. The flock house virus is a member of the Nodaviridae family. It kills the New Zealand grass grub insect

Background imageAlpha Helix Collection: Xylose isomerase complex F006 / 9765

Xylose isomerase complex F006 / 9765
Xylose isomerase complex. Molecular model of the enzyme D-xylose isomerase bound to the sugar alcohol sorbitol. D-xylose isomerase is involved in fructose and mannose metabolism

Background imageAlpha Helix Collection: H-Ras p21 oncogene protein F006 / 9766

H-Ras p21 oncogene protein F006 / 9766
H-Ras p21 oncogene protein, molecular model. The Ras proteins are involved in transmitting signals within cells. Excessive signalling can lead to conditions such as cancer

Background imageAlpha Helix Collection: Phosphofructokinase bacterial enzyme F006 / 9762

Phosphofructokinase bacterial enzyme F006 / 9762
Phosphofructokinase enzyme, molecular model. This enzyme, from the bacterium Bacillus stearothermophilus, is involved in regulating the process of releasing energy from glucose

Background imageAlpha Helix Collection: tRNA molecule F006 / 9764

tRNA molecule F006 / 9764
Transfer RNA (tRNA), molecular model. tRNA (transfer ribonucleic acid) translates messenger RNA (mRNA) into a protein product

Background imageAlpha Helix Collection: H-Ras p21 oncogene protein F006 / 9763

H-Ras p21 oncogene protein F006 / 9763
H-Ras p21 oncogene protein, molecular model. The Ras proteins are involved in transmitting signals within cells. Excessive signalling can lead to conditions such as cancer

Background imageAlpha Helix Collection: Kinase inhibitor complex F006 / 9760

Kinase inhibitor complex F006 / 9760
Kinase inhibitor complex. Molecular model of a leucettine kinase inhibitor bound to a serine threonine kinase protein

Background imageAlpha Helix Collection: Marburg viral protein 35 and RNA F006 / 9759

Marburg viral protein 35 and RNA F006 / 9759
Marburg viral protein 35 and RNA. Molecular model of the Marburg viral protein 35 (VP35) bound to a molecule of double stranded RNA (ribonucleic acid)

Background imageAlpha Helix Collection: Insulin molecule F006 / 9761

Insulin molecule F006 / 9761
Insulin molecule. Molecular model of the hormone insulin from a pig. Insulin consists of two peptide chains, A and B, which are linked by disulphide bridges

Background imageAlpha Helix Collection: Eye lens protein molecule F006 / 9758

Eye lens protein molecule F006 / 9758
Eye lens protein. Molecular model of gammaB-crystallin, a protein found in the lens of the eye. The regular arrangement of the protein in the lens is thought to be responsible for its transparency

Background imageAlpha Helix Collection: Methionine aminopeptidase molecule F006 / 9756

Methionine aminopeptidase molecule F006 / 9756
Methionine aminopeptidase, molecular model. This enzyme removes the amino acid methionine from proteins

Background imageAlpha Helix Collection: Hepatitis C glycoprotein and antibody F006 / 9757

Hepatitis C glycoprotein and antibody F006 / 9757
Hepatitis C glycoprotein and antibody. Molecular model of the E2 envelope glycoprotein from the hepatitis C virus bound to a neutralising antibody

Background imageAlpha Helix Collection: Malignant brain-tumor-like protein F006 / 9754

Malignant brain-tumor-like protein F006 / 9754
Malignant brain-tumour-like protein. Molecular model of the human lethal(3) malignant brain-tumour-like protein (Malignant brain-tumour-like protein (L3MBTL3)

Background imageAlpha Helix Collection: Guanine-responsive riboswitch F006 / 9753

Guanine-responsive riboswitch F006 / 9753
Guanine-responsive riboswitch, molecular model. This protein regulates gene expression by binding to the nucleotide guanine to switch off transcription

Background imageAlpha Helix Collection: UV-damaged DNA-binding protein and DNA F006 / 9750

UV-damaged DNA-binding protein and DNA F006 / 9750
UV-damaged DNA-binding protein and DNA. Molecular model of UV-damaged DNA-binding protein (UV-DDB) complexed with DNA (deoxyribonucleic acid, red and blue)

Background imageAlpha Helix Collection: Plexin signal transduction molecule F006 / 9751

Plexin signal transduction molecule F006 / 9751
Plexin signal transduction molecule. Molecular model of plexin-A4 a signal transduction protein that is involved in neural maintenance and regeneration



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The alpha helix, a fundamental structure in biology, plays a crucial role in various molecular processes. From DNA transcription to protein synthesis, this intricate arrangement is found throughout the biological world. In the realm of genetics, the alpha helix participates in DNA transcription by aiding in the unwinding and separation of strands. Its elegant spiral shape allows for efficient reading and copying of genetic information. When it comes to proteins, the alpha helix serves as a secondary structure that contributes to their stability and function. Visualized through stunning artwork or molecular models, its coiled form adds strength and flexibility to these vital biomolecules. One example where we can observe this remarkable structure is within the nucleosome molecule. Here, DNA wraps around histone proteins forming tight coils resembling beads on a string – with each bead representing an alpha helix. Another instance occurs within bacterial ribosomes responsible for protein synthesis. The presence of multiple alpha helices enables precise positioning of molecules during translation – ensuring accurate assembly of amino acids into functional proteins. Viruses also exploit this structural motif; one such case being HIV reverse transcription enzyme. This enzyme utilizes an alpha helical region to convert viral RNA into DNA – a critical step in viral replication. Similarly, hepatitis C virus enzyme employs an intricate network of alpha helices depicted by molecular models. These structures aid in catalyzing chemical reactions necessary for viral survival and proliferation. Moving beyond viruses, manganese superoxide dismutase enzyme showcases how nature harnesses the power of the alpha helix for antioxidant defense mechanisms within cells. Its tightly wound coils protect against harmful free radicals that can damage cellular components. Alpha-helical motifs are not limited to enzymes alone but extend to larger molecules like human serum albumin or Argonaute protein involved in gene regulation pathways. Their well-defined arrangements contribute significantly to their respective functions within our bodies' complex systems.