Tumour suppressor protein with DNA F006 / 9523
Wall Art and Photo Gifts from Science Photo Library
Tumour suppressor protein with DNA F006 / 9523
Tumour suppressor protein. Molecular model of the tumour suppressor protein p53 (beige) bound to a molecule of DNA (deoxyribonucleic acid, red and blue). P53 prevents the proliferation of cells with damaged DNA. Its production occurs in response to radiation and chemicals that damage the structure of DNA. The protein binds to specific sequences in the DNA and halts the cell cycle (the means by which cells replicate). If there is only minor damage p53 activates genes involved in DNA repair, but if the damage cannot be repaired it initiates cell death (apoptosis). P53 plays a very important role in preventing the replication of cancerous cells, so much so that p53 is found to be inactive in 50% of all cancers
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 9255679
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Alpha Helix Anti Cancer Beta Sheet Cell Cycle Checkpoint Factor Dna Repair Homotetramer Protection Protective Proteomics Strand Tertiary Structure Transcriptional Activator Tumour Suppressor Protein Biochemical Biochemistry Cutouts Deoxyribonucleic Acid Genetics Molecular Molecular Model Molecular Structure Protein
EDITORS COMMENTS
This print showcases the intricate molecular model of the tumour suppressor protein p53, bound to a molecule of DNA. The beige-coloured p53 protein is depicted alongside the red and blue strands of DNA, representing its crucial role in preventing cell proliferation when DNA damage occurs. When exposed to radiation or chemicals that harm DNA structure, p53 production is triggered as a protective response. This remarkable protein binds to specific sequences within the DNA, effectively halting the cell cycle responsible for replication. In cases where minor damage exists, p53 activates genes involved in repairing DNA; however, if repair is impossible, it initiates programmed cell death known as apoptosis. P53's significance lies in its pivotal role in preventing cancerous cells from replicating. Astonishingly though, this vital protector remains inactive in approximately 50% of all cancers. The white background accentuates the detailed illustration's focus on this essential biological process occurring at a molecular level. It serves as a reminder of how research and medicine continuously strive to understand and harness these mechanisms for improved healthcare outcomes. This image represents not only an artistic portrayal but also highlights key concepts such as genetics, biochemistry, proteomics and medical illustration associated with tumour suppressor proteins like p53. Its presence serves as a testament to ongoing efforts aimed at unraveling the complexities underlying cancer development while emphasizing potential therapeutic avenues for combating this devastating disease.
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