Renin and inhibitor complex
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Renin and inhibitor complex
Renin and inhibitor complex. Computer model showing the secondary structure of the enzyme renin complexed with inhibitor 7. Beta sheets (arrows), alpha helices (coils) and random coils (wires) can be seen. Renin is produced by the kidneys. It is part of the renin-angiotensin-aldosterone pathway that is responsible for controlling blood pressure by balancing sodium and potassium levels in the blood, and fluid levels in the body. Too much renin can cause high blood pressure, therefore various inhibitors have been created to block its action. Inhibitor-7 is one of these
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6299879
© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY
Alpha Helix Beta Sheet Blood Pressure Coils Complex Complexed Compound Drug Endocrine Endocrinology Enzyme Helixes Hormonal Inhibiting Inhibition Level Levels Molecular Biology Peptide Physiological Proteomics Random Coil Regulation Regulator Renal Secondary Structure Sheets Bio Chemistry Biochemical Molecular Model Molecular Structure
EDITORS COMMENTS
This print showcases a computer-generated model of the renin and inhibitor complex, revealing the intricate secondary structure of this vital enzyme. Against a pristine white background, one can observe the distinct features including beta sheets represented by arrows, alpha helices depicted as coils, and random coils illustrated as wires. Renin is primarily synthesized in the kidneys and plays a crucial role in maintaining blood pressure equilibrium through its involvement in the renin-angiotensin-aldosterone pathway. This pathway regulates sodium and potassium levels within the bloodstream while also managing fluid balance throughout the body. However, excessive production of renin can lead to hypertension or high blood pressure. To counteract this effect, scientists have developed various inhibitors like Inhibitor-7 to impede renin's action. By blocking its activity, these inhibitors help maintain optimal blood pressure levels. The photograph provides an insightful glimpse into molecular biology and biochemistry by showcasing how proteins interact at a microscopic level. It highlights both the complexity and elegance of biological systems that govern our physiological processes. With its focus on molecular structures such as peptides, alpha helices, beta sheets, and random coils, this image serves as a valuable resource for researchers studying proteomics or those interested in understanding how enzymes function at a molecular level within our bodies.
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