Lysyl oxidase enzyme molecule
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Lysyl oxidase enzyme molecule
Lysyl oxidase enzyme molecule. Computer artwork showing the secondary structure of the enzyme lysyl oxidase (LOX). LOX is a homodimeric (composed of two identical subunits) enzyme that modifies collagen and elastin proteins so that they can crosslink, thus stabilising deposits of these proteins in the extracellular matrix (ECM). The ECM acts as a barrier and separates different cell types within tissues. It also provides structural support and regulates intercellular communication. This LOX enzyme is from a yeast (Pichia pastoris), and although structurally different from mammalian LOX, it is functionally the same
Science Photo Library features Science and Medical images including photos and illustrations
Media ID 6308385
© DR MARK J. WINTER/SCIENCE PHOTO LIBRARY
Compound Compounds Dimer Dimeric Enzyme Enzymes Extracellular Matrix Helices Homodimer Molecules Proteomics Secondary Structure Sheets Structural Sub Unit Subunits Yeast Bio Chemistry Biochemical Molecular Protein
EDITORS COMMENTS
This print showcases the intricate beauty of the Lysyl oxidase enzyme molecule. Through computer artwork, the secondary structure of this remarkable enzyme is revealed in stunning detail. Lysyl oxidase (LOX) is a homodimeric enzyme composed of two identical subunits, and its primary function lies in modifying collagen and elastin proteins within the extracellular matrix (ECM). By crosslinking these proteins, LOX plays a crucial role in stabilizing their deposits, which are essential for maintaining tissue integrity. The ECM acts as a vital barrier that separates different cell types while providing structural support and regulating intercellular communication. This image allows us to appreciate how LOX contributes to these fundamental processes on a molecular level. Although this particular LOX enzyme originates from yeast (Pichia pastoris), it shares functional similarities with mammalian LOX despite its structural differences. The complexity and elegance of this molecule highlight the wonders of biochemistry and proteomics. Displayed against a white background, the black-and-white illustration emphasizes both simplicity and sophistication simultaneously. This print serves as an inspiring reminder of nature's intricate design at microscopic scales—a testament to the beauty found within biological systems.
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