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Tumour suppressor protein and DNA C017 / 3644

Tumour suppressor protein and DNA C017  /  3644


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Tumour suppressor protein and DNA C017 / 3644

Tumour suppressor protein and DNA. Computer artwork showing a molecule of the tumour suppressor protein p53 (blue and pink) bound to a molecule of DNA (deoxyribonucleic acid, yellow and orange). p53 is crucial in multicellular organisms, where it regulates the cell cycle (the means by which cells replicate) and prevents the proliferation of cells with damaged DNA. It is produced in response to radiation and chemicals that damage the structure of DNA, when it binds to specific sequences in the DNA and halts the cell cycle. If there is only minor damage, p53 activates genes involved in DNA repair, but if the damage cannot be repaired it initiates cell death (apoptosis). p53 plays a very important role in preventing the replication of cancerous cells, so

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9340903

© RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Binding Bound Cell Cycle Complex Complexed Gene Genes Genetic Molecules Preventative Prevention Proteins Proteomics Quaternary Structure Secondary Structure Strand Tertiary Structure Tumor Suppressor Tumour Suppressor Protein Biochemical Biochemistry Deoxyribonucleic Acid Genetics Molecular Model Protein


EDITORS COMMENTS
This print showcases the intricate relationship between a tumour suppressor protein and DNA. In this computer artwork, we witness the molecular dance of p53, a crucial protein found in multicellular organisms. Colored in shades of blue and pink, p53 is seen bound to DNA molecules represented by vibrant yellow and orange hues. The significance of p53 lies in its ability to regulate the cell cycle, preventing damaged cells from proliferating. When exposed to radiation or chemicals that harm DNA structure, p53 binds specifically to sequences within the DNA strands, effectively halting the replication process. If only minor damage occurs, p53 activates genes responsible for DNA repair; however, if irreparable damage is detected, it initiates programmed cell death known as apoptosis. Through its role in preventing cancerous cell replication, p53 emerges as a key player in safeguarding our genetic material. This stunning illustration highlights not only its structural complexity but also its vital function within our bodies. Created by RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY with a white background and an emphasis on genetic structures such as proteins and genes intertwined with molecules of deoxyribonucleic acid (DNA), this artwork delves into the world of biochemistry and proteomics. It serves as a reminder of how scientific imagery can captivate us while unraveling essential mechanisms that shape life itself.

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