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Ulcerative colitis, SEM

Ulcerative colitis, SEM


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Ulcerative colitis, SEM

Ulcerative colitis. Coloured scanning electron micrograph (SEM) of freeze-fractured bowel tissue from a patient suffering from ulcerative colitis. The fracture plane has passed through the walls of a tubular gland, leaving the space (lumen) between the walls (lower left to top right) surrounded by a section through these walls. This section shows that the wall comprises columnar absorptive cells that absorb nutrients through the microvilli on their surface. This surface is partly visible in the lumen. The absence of mucus-secreting goblet cells is a characteristic of ulcerative colitis, which is the inflammation and ulceration of the colon and rectum. Magnification unknown

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 6413569

© STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY

Alimentary Canal Bowel Colon Digestion Digestive System Fracture Fractured Freeze Fracture Freeze Fractured Glandular Histology Histopathology Inflamed Intestinal Large Intestine Mucosa Pathology Tissue Ulcer Ulcerated Ulcerative Colitis Ulcers Condition Disorder Health Care


EDITORS COMMENTS
This print from Science Photo Library offers a close-up view of ulcerative colitis, a debilitating condition affecting the colon and rectum. The image showcases freeze-fractured bowel tissue taken from a patient suffering from this inflammatory disorder. As we delve into the intricate details captured by scanning electron microscopy (SEM), we witness the aftermath of an inflammation-induced fracture that has passed through the walls of a tubular gland. The space between these fractured walls, visible in shades of vibrant color, reveals columnar absorptive cells responsible for nutrient absorption through their microvilli-covered surface. However, what strikes us is the absence of mucus-secreting goblet cells—a hallmark characteristic of ulcerative colitis. This SEM image provides valuable insights into the histopathology and anatomy associated with this disease. It highlights how ulcers form within the mucosal surface and underscores the impact on overall digestive health. While magnification remains unknown, its ability to capture such minute structures emphasizes its significance in medical research and diagnosis. Ulcerative colitis poses significant challenges for patients who endure chronic inflammation and ulceration within their intestinal tract. This image serves as a reminder of both the complexity involved in understanding this disorder and our ongoing commitment to advancing healthcare solutions for those affected by it.

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