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Insulin receptor molecule C015 / 9405

Insulin receptor molecule C015  /  9405


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Insulin receptor molecule C015 / 9405

Insulin receptor, molecular model. The insulin receptor is a transmembrane protein, that is it spans the cellular membrane. The part of the receptor that sits on the outside of the cell, the ectodomain, is seen here, complexed with the antigen-binding fragment (Fab) of an antibody. Binding of insulin to the extracellular part of the protein activates a number of changes inside the cell that lead to the uptake of glucose, the synthesis of glycogen and fatty acids and glycolysis, the production of energy from glucose

Science Photo Library features Science and Medical images including photos and illustrations

Media ID 9238601

© LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Antibody Antigen Binding Fragment Complexed Dimer Extracellular Metabolism Proteomics Receptor Signal Transduction Spacefill Spacefilled Transmembrane Protein Tyrosine Kinase Biochemical Biochemistry Cutouts Molecular Molecular Model Protein


EDITORS COMMENTS
This print showcases the intricate structure of the insulin receptor molecule, known as C015 / 9405. The insulin receptor is a remarkable transmembrane protein that spans across the cellular membrane. In this image, we can observe the ectodomain of the receptor, which resides on the outer side of the cell. It is fascinating to see how it interacts with an antibody's antigen-binding fragment (Fab), forming a complex. The binding of insulin to this extracellular part triggers a cascade of events inside the cell that play crucial roles in glucose regulation and metabolism. These include glucose uptake, glycogen and fatty acid synthesis, as well as glycolysis - which generates energy from glucose. Displayed against a pristine white background, this illustration highlights various aspects essential for understanding biological processes at a molecular level. With its cut-out design and detailed depiction, it offers valuable insights into proteomics, signal transduction pathways, tyrosine kinase activity, dimer formation, and other vital aspects related to insulin signaling. Created by LAGUNA DESIGN/SCIENCE PHOTO LIBRARY with meticulous attention to detail and accuracy in representing this complex biological system; this artwork serves as an invaluable resource for researchers delving into biochemistry or studying glucose homeostasis mechanisms.

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