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Reovirus Collection

Reoviruses, members of the Reoviridae family, are non-enveloped double-stranded RNA viruses with a unique icosahedral symmetry


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Reoviruses, members of the Reoviridae family, are non-enveloped double-stranded RNA viruses with a unique icosahedral symmetry. In this cutaway view, observe the complex architecture of a reovirus particle, revealing its 10 segments of double-stranded RNA encased within. Rotaviruses, a type of reovirus, are the leading cause of gastrointestinal infections in children worldwide. As seen in this microscopic image (TEM C016 / 9443), rotavirus particles display a wheel-like structure with spikes on their surface. The molecular model illustrates the intricate details of a single reovirus particle, including its capsid proteins and the Sigma1 protein (artwork C016 / 9331) that plays a crucial role in virus entry into host cells. Inside the cell, reovirus particles replicate, as shown in this coloured TEM image (TEM), leading to the release of new virions. Rotavirus particles, like those depicted in this artwork (C016 / 9330), continue their infectious cycle, contributing to the spread of this common viral infection.