Proteomics Collection (page 9)

Voltage-gated potassium channel F006 / 9562
Voltage-gated potassium (Kv) ion channel, molecular model. Ion channels are membrane-spanning proteins that form pores in cell membranes

Tumour suppressor protein with DNA F006 / 9564
Tumour suppressor protein. Molecular model of the tumour suppressor protein p53 (beige) bound to a molecule of DNA (deoxyribonucleic acid, red and blue)

Ricin molecule F006 / 9563
Ricin. Molecular model of the toxic protein ricin. It comprises two entwined amino acid chains, termed A and B. The A-chain is toxic, inhibiting protein synthesis in cells

DNA tetranucleosome, molecular model F006 / 9555
DNA tetranucleosome. Molecular model of four nucleosomes, or a tetranucleosome. Nucleosomes are the fundamental repeating unit used to package DNA (deoxyribonucleic acid) inside cell nuclei

Thrombin complexed with fibrinogen F006 / 9561
Thrombin complexed with fibrinogen, molecular model. The thrombin molecules (beige, right and left) are bound to the central part of the fibrinogen molecule (down centre)

SARS virus surface protein molecule F006 / 9560
SARS virus surface protein. Molecular model of the spike 2 (S2) envelope glycoprotein from the severe acute respiratory syndrome (SARS) virus

DNA polymerase with DNA F006 / 9559
DNA polymerase with DNA. Molecular model of human DNA polymerase beta (beige) complexed with a molecule of DNA (deoxyribonucleic acid, red and blue)

Insulin molecule F006 / 9558
Insulin, molecular model. Insulin plays an important role in blood sugar regulation. It is released from the pancreas when blood sugar levels are high, for example after a meal

Bacteriophage DNA recombination F006 / 9554
Bacteriophage DNA recombination. Molecular model showing DNA manipulation and recombination taking place at a Holliday junction with a bacteriophage enzyme

ATP-dependent protease molecule F006 / 9552
ATP-dependent protease. Molecular model of the bacterial enzyme HsIUV protease. Proteases are enzymes that break down proteins. HsIUV is expressed in response to cellular stress

Zinc finger molecule F006 / 9557
Zinc finger, molecular model. Zinc fingers constitute the DNA recognition domains of many DNA regulatory proteins and are so named for their resemblance to fingers projecting from the protein

Botulinum type B neurotoxin F006 / 9553
Botulinum type B neurotoxin, molecular model. This powerful toxin, produced by the bacterium Clostridium botulinum, enters nerve cells and prevents release of neurotransmitters

TATA box-binding protein complex F006 / 9551
TATA box-binding protein complex. Molecular model showing a yeast TATA box-binding protein (TBP) complexed with a strand of DNA (deoxyribonucleic acid, red and blue) and transcription factor IIA

NADP-dependent alcohol dehydrogenase F006 / 9549
NADP-dependent alcohol dehydrogenase, molecular model. Alcohol dehydrogenase (ADH) is an enzyme that facilitates the break-down of alcohols in the body, which could otherwise be toxic

TATA box-binding protein and DNA F006 / 9550
TATA box-binding protein and DNA. Molecular model showing a TATA box-binding protein (TBP) complexed with a strand of DNA (deoxyribonucleic acid, red and blue)

Cholera toxin molecule F006 / 9546
Cholera toxin, molecular model. Cholera toxin is a protein complex secreted by the bacterium Vibrio cholerae, that causes the disease cholera

Programmed cell death protein 6 molecule F006 / 9548
Programmed cell death protein 6, molecular model. This is a calcium-binding protein is involved in apoptosis (programmed cell death)

GATA transcription factor and zinc finger F006 / 9547
GATA transcription factor. Molecular model of the GATA transcription factor bound to a zinc finger. Transcription factors are proteins that bind to specific DNA sequences

Plant hormone regulator, molecular model F006 / 9545
Plant hormone regulator. Molecular model of Ia-amidohydrolase from thale cress (Arabidopsis thaliana). This enzyme acts to release the plant hormone indoe-3-acetic acid from its storage form

Hydroxysteroid dehydrogenase molecule F006 / 9543
Hydroxysteroid dehydrogenase. Molecular model of the human type 5 hydroxysteroid dehydrogenase enzyme bound to a molecule of the steroid drug androstene

RNA stem-loop motif, molecular model F006 / 9544
RNA stem-loop motif. Molecular model of the stem-loop II motif from the SARS (severe acute respiratory syndrome) coronavirus. This RNA (ribonucleic acid) element is a target for antiviral drugs

Nerve growth factor bound to receptor F006 / 9541
Nerve growth factor bound to receptor, molecular model. Human nerve growth factor bound to the TrkA receptor. NGF is a neurotrophin that acts on the development and function of nerves

DNA binding protein, molecular model F006 / 9540
DNA binding protein. Molecular model of the recombinant protein S7dLZ bound to DNA (deoxyribonucleic acid) molecules. S7dLZ is made up of the DNA binding protein Sac7d

Pyruvate dehydrogenase enzyme molecule F006 / 9538
Pyruvate dehydrogenase (E1), molecular model. This enzyme converts pyruvate to acetyl-CoA for use in the citric acid (or Krebs) cycle

Elongation factor Tu and tRNA F006 / 9522
Elongation factor Tu bound to tRNA (transfer ribonucleic acid), molecular model. This enzyme is involved in the elongation of polypeptide chains during translation

Fish antifreeze protein F006 / 9539
Fish antifreeze protein. Molecular model of a fish antifreeze protein (AFP) from the winter flounder (Pseudopleuronectes americanus)

Bacteriophage ATPase molecule F006 / 9536
Bacteriophage ATPase. Molecular model of an ATP synthase (ATPase) molecule from the phi 12 bacteriophage. ATPase is an important enzyme that provides energy for cells through the synthesis of

Molecular motor protein F006 / 9537
Molecular motor protein. Molecular model of a two-headed motor protein, Myosin V. Motor proteins convert chemical energy into mechanical movements in response to specific chemical stimuli

Cytochrome b6f complex, molecular model F006 / 9533
Cytochrome b6f complex, molecular model. Cytochrome molecules perform oxidation and reduction reactions for electron transport

Glycosylation enzyme molecule F006 / 9535
Glycosylation enzyme. Molecular model of the enzyme N-acetylglucosamine (GlcNAc) transferase. This intracellular enzyme adds N-acetylglucosamine molecules to target proteins

TATA box-binding protein complex F006 / 9534
TATA box-binding protein complex. Molecular model showing a yeast TATA box-binding protein (TBP) complexed with a strand of DNA (deoxyribonucleic acid, red and blue) and transcription factor IIB

Transcription factor and ribosomal RNA F006 / 9530
Transcription factor and ribosomal RNA (rRNA). Molecular model showing the 6 zinc fingers of transcription factor IIIA (yellow) bound to RNA (ribonucleic acid)

Bacteriophage restriction enzyme F006 / 9531
Bacteriophage restriction enzyme. Molecular model of the restriction enzyme endonuclease V (yellow) from the bacteriophage T4 complexed with DNA (deoxyribonucleic acid, red and blue)

Squalene-hopene cyclase molecule F006 / 9529
Squalene-hopene cyclase, molecular model. This bacterial enzyme catalyses the cyclization of squalene to hopene

Self-splicing RNA intron, molecular model F006 / 9527
Self-splicing RNA intron, molecular model. Splicing is the process where a non-coding fragment (intron) of a strand of nucleic acid (DNA, deoxyribonucleic acid; or RNA, ribonucleic acid) is removed

Ubiquitin molecule F006 / 9528
Ubiquitin, molecular model. Ubiquitin is found in all eukaryotic cells. When a protein is damaged or old it will be tagged by several ubiquitin molecules

Cobra venom molecule F006 / 9524
Cobra venom. Molecular model of toxin b, a long neurotoxin from a king cobra (Ophiophagus hannah)

Tumour suppressor protein with DNA F006 / 9523
Tumour suppressor protein. Molecular model of the tumour suppressor protein p53 (beige) bound to a molecule of DNA (deoxyribonucleic acid, red and blue)

Tarantula toxin molecule F006 / 9525
Tarantula toxin. Molecular model of a peptide toxin from the tarantula Grammostola spatulata. This toxin works by inhibiting mechanosensitive ion channels

Nitric oxide synthase molecule F006 / 9521
Nitric oxide synthase, molecular model. This enzyme catalyses the production of nitric oxide from L-arginine. Nitric oxide is involved in cellular signalling

LAC repressor molecule F006 / 9520
LAC repressor. Molecular model of a LAC (lactose) repressor molecule. The LAC repressor inhibits the expression of genes that code for an enzyme which metabolizes lactose in bacteria

SV40 virus capsid, molecular model F006 / 9508
SV40 virus capsid, molecular model. Simian virus 40 (SV40) is found in monkeys such as Rhesus monkeys and macaques. Potentially tumour-causing, it is used in laboratory research and in vaccines

Carbonic anhydrase molecule F006 / 9518
Carbonic anhydrase, molecular model. This enzyme catalyses the reversible hydration of carbon dioxide

Reverse transcriptase and inhibitor F006 / 9519
Reverse transcriptase and inhibitor. Molecular model of HIV reverse transcriptase complexed with a non-nucleoside reverse transcriptase inhibitor drug

Transducin protein beta-gamma complex F006 / 9514
Transducin protein beta-gamma complex. Molecular model of the beta-gamma dimer of the heterotrimeric G protein transducin

Trypsinogen molecule with inhibitor F006 / 9517
Trypsinogen molecule. Molecular model of trypsinogen, the precursor to the digestive protease enzyme trypsin, complexed with an inhibitor

Transcription factor and ribosomal RNA F006 / 9516
Transcription factor and ribosomal RNA (rRNA). Molecular model showing the 6 zinc fingers of transcription factor IIIA (yellow) bound to RNA (ribonucleic acid)

T cell receptor, molecular model F006 / 9515
T cell receptor. Molecular model of an alpha T cell receptor. T cell receptors are protein complexes found on the surface of a type of white blood cell called T lymphocytes (or T cells)

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Proteomics, the study of proteins and their functions within an organism, is a fascinating field that unravels the intricate workings of life. From anaesthetics inhibiting ion channels to immunoglobulin G antibody molecules, proteomics delves into the molecular mechanisms that shape our existence. In the realm of brain research, scientists explore how proteins influence cognition and behavior. They investigate DNA nucleosomes' structure and function, unraveling their role in gene regulation. Antibodies take center stage as artwork showcases their diverse forms and crucial role in immune defense. Zinc fingers bound to a DNA strand highlight protein-DNA interactions critical for genetic processes. Meanwhile, manganese superoxide dismutase enzyme aids in protecting cells from oxidative stress. The SARS coronavirus protein becomes a subject of intense scrutiny as researchers strive to understand its pathogenicity. Cytochrome b5 molecule reveals insights into electron transfer reactions within cells while glutamine synthetase enzyme plays a vital role in nitrogen metabolism. Lastly, RNA-editing enzymes offer potential therapeutic targets for various diseases with their ability to modify genetic information at the RNA level. Through proteomics, we unlock nature's secrets one protein at a time - deciphering their structures, unraveling their functions, and ultimately enhancing our understanding of life itself.