Endonuclease Collection

Flap endonuclease protein F007 / 9914
Molecular model of the flap endonuclease protein. This is a class of nucleolytic enzymes that act as both 5 -3 exonucleases

Flap endonuclease protein F007 / 9916
Molecular model of the flap endonuclease protein. This is a class of nucleolytic enzymes that act as both exonucleases and structure-specific endonucleases on specialised DNA structures that occur

RNA exosome complex, molecular model F006 / 9620
RNA exosome complex, molecular model. This multi-protein complex functions to break up strands of RNA (ribonucleic acid, pink) during biochemical processes

RNA interference protein, molecular model F006 / 9589
RNA interference protein, molecular model. This RNA interference protein is also known as dicer. It is an RNAase enzyme that cleaves double-stranded RNA into short fragments called small interfering

Endonuclease and DNA, molecular model F006 / 9413
Endonuclease and DNA. Molecular model of an endonuclease restriction enzyme (yellow) bound to a molecule of DNA (deoxyribonucleic acid)

Restriction enzyme and DNA F006 / 9315
Restriction enzyme and DNA. Molecular model showing an EcoRI endonuclease enzyme (purple and green) bound to a DNA (deoxyribonucleic acid) molecule (red and blue)

Exosome complex, molecular model. This multi-protein complex functions to break up strands of RNA (ribonucleic acid, pink) during biochemical processes

Restriction enzyme and DNA, illustration C018 / 0785
Restriction enzyme. Illustration of a restriction enzyme (green) complexed with DNA (deoxyribonucleic acid, across centre)

Restriction enzyme cutting DNA
Fragment of DNA bound by the restriction endonucleaseEcoRI. The protein is a dimer, with each subunitable to bind and cut one strand of DNA

Restriction enzyme and DNA C015 / 6941
Restriction enzyme and DNA. Molecular model showing an EcoRI endonuclease enzyme (purple) bound to a DNA (deoxyribonucleic acid) strand (blue). EcoRI is an enzyme isolated from strains of E

Influenza endonuclease enzyme molecule C016 / 2683
Influenza endonuclease enzyme. Molecular model of the PA protein from the influenza virus. This endonuclease enzyme is essential for viral replication

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"Exploring the Intricate World of Endonucleases: Unveiling the Molecular Models and Illustrations" In the realm of molecular biology, endonucleases play a pivotal role in DNA replication, repair, and gene regulation. Among them, Flap endonuclease proteins F007/9914 and F007/9916 stand out as key players in resolving DNA structures during replication. Their intricate structure allows them to precisely cleave single-stranded flaps that arise during this crucial process. Another remarkable entity is the RNA exosome complex (molecular model F006/9620), which acts as a cellular "garbage disposal, " degrading unwanted RNA molecules with exceptional precision. Its composition comprises multiple subunits working together harmoniously to maintain cellular homeostasis. The fascinating world of RNA interference unfolds with its own protagonist - an RNA interference protein (molecular model F006/9589). This molecule orchestrates a sophisticated mechanism that regulates gene expression by silencing specific target genes through mRNA degradation or translational inhibition. Endonucleases also exhibit their prowess when it comes to DNA manipulation. Molecular models such as F006/9413 showcase how these enzymes proficiently cleave double-stranded DNA at specific recognition sites, enabling genetic engineering techniques like gene splicing or fragment analysis. Restriction enzymes are another class of endonucleases that have revolutionized molecular biology research. The illustration C018/0785 depicts their interaction with DNA, highlighting their ability to recognize specific sequences and cut them precisely. These enzymes find extensive use in cloning experiments and genotyping analyses due to their sequence-specific nature. Delving deeper into restriction enzyme action reveals captivating visuals captured by illustrations like C015/6941 showcasing restriction enzymes cutting through DNA strands meticulously. Such images provide insights into how these powerful tools enable scientists to manipulate genetic material for various applications ranging from disease diagnosis to recombinant protein production.