Antimalarial Collection

Amargo, bitter-ash or bitter-wood, Quassia amara. Handcoloured copperplate engraving from Dr
FLO4563931 Amargo, bitter-ash or bitter-wood, Quassia amara. Handcoloured copperplate engraving from Dr. Willibald Artus Hand-Atlas sammtlicher mediinisch-pharmaceutischer Gewachse

Amargo, bitter-ash or bitter-wood, Quassia amara. Handcoloured copperplate engraving from Dr. Willibald Artus Hand-Atlas sammtlicher mediinisch-pharmaceutischer Gewachse

WW1 - The advantages of using Quinine to treat illness
WW1 - Soldier! Take your daily quinine - the advantages of using Quinine to treat illness, due to its antipyretic (fever-reducing), antimalarial, analgesic (painkilling)

Malaria drug dispensing, World War II C016 / 4303
Malaria drug dispensing. Close-up of the antimalarial drug atabrine being distributed during World War II (1939-1945) according to a checklist

Malaria drug warning, World War II C016 / 4301
Malaria drug warning. Skulls on a warning sign at a US Army hospital during World War II (1939-1945). Also known as quinacrine and mepacrine

Cinchona officianalis illustration, quinine
From the Plate Collection of the Natural History Museum, London

Quinine malaria drug molecule
Quinine malaria drug, molecular model. Quinine is obtained from the bark of the cinchona tree (Cinchona sp.), which is native to South America. It has been used to treat malaria for over 300 years

Artemisia flowers (Artemisia sp.) clustered on a branch. The Artemisia plants have many medicinal properties, with some being used to prepare drugs to treat malaria

Artemisinin malaria drug molecules. Computer artwork of molecules of the malaria drug artemisinin in the bloodstream. This drug is effective against populations of the malaria parasite

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"Antimalarial: A Bitter-Sweet Remedy for a Deadly Disease" In the world of medicine, few substances have had such a profound impact on combating malaria as antimalarials. Derived from various sources, these potent remedies have saved countless lives throughout history. One such source is Amargo, also known as bitter-ash or bitter-wood (Quassia amara). This tropical plant has long been recognized for its medicinal properties and was used by indigenous tribes to treat fevers and digestive ailments. Little did they know that it contained compounds effective against the malaria parasite. Another remarkable discovery came in the late 19th century with the Quinine Tree (Cinchona Calisaya). Its bark yielded quinine, an essential compound in treating malaria. The beautiful chromolithograph from 1890 showcases this tree's significance in providing relief to those suffering from this devastating disease. During World War I, quinine proved invaluable in treating soldiers afflicted with malaria. Its advantages were evident - reducing fever and preventing relapses. Thanks to this wonder drug, many lives were spared amidst the chaos of war. As World War II raged on, efforts intensified to dispense malaria drugs efficiently among troops stationed in affected regions. Malaria drug dispensing stations became crucial hubs where soldiers received their life-saving doses of medication like clockwork. However, even with advancements in antimalarials came warnings about potential side effects during wartime conditions. Soldiers were cautioned about adverse reactions and instructed on proper usage to ensure maximum efficacy while minimizing risks. The cinchona officinalis illustration serves as a reminder of quinine's origin and its role as a powerful weapon against malaria. The intricate depiction captures both its botanical beauty and scientific importance simultaneously. Zooming into molecular structures reveals the complexity behind these antimalarial wonders – multiple representations of quinine molecules emphasize their pivotal role in disrupting the parasite's life cycle within human hosts. But the fight against malaria didn't stop there.