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Alpha Helix Collection (page 6)

The alpha helix, a fundamental structure in biology, plays a crucial role in various molecular processes

Background imageAlpha Helix Collection: RNA stem-loop motif, molecular model F006 / 9544

RNA stem-loop motif, molecular model F006 / 9544
RNA stem-loop motif. Molecular model of the stem-loop II motif from the SARS (severe acute respiratory syndrome) coronavirus. This RNA (ribonucleic acid) element is a target for antiviral drugs

Background imageAlpha Helix Collection: Nerve growth factor bound to receptor F006 / 9541

Nerve growth factor bound to receptor F006 / 9541
Nerve growth factor bound to receptor, molecular model. Human nerve growth factor bound to the TrkA receptor. NGF is a neurotrophin that acts on the development and function of nerves

Background imageAlpha Helix Collection: DNA binding protein, molecular model F006 / 9540

DNA binding protein, molecular model F006 / 9540
DNA binding protein. Molecular model of the recombinant protein S7dLZ bound to DNA (deoxyribonucleic acid) molecules. S7dLZ is made up of the DNA binding protein Sac7d

Background imageAlpha Helix Collection: Pyruvate dehydrogenase enzyme molecule F006 / 9538

Pyruvate dehydrogenase enzyme molecule F006 / 9538
Pyruvate dehydrogenase (E1), molecular model. This enzyme converts pyruvate to acetyl-CoA for use in the citric acid (or Krebs) cycle

Background imageAlpha Helix Collection: Elongation factor Tu and tRNA F006 / 9522

Elongation factor Tu and tRNA F006 / 9522
Elongation factor Tu bound to tRNA (transfer ribonucleic acid), molecular model. This enzyme is involved in the elongation of polypeptide chains during translation

Background imageAlpha Helix Collection: Fish antifreeze protein F006 / 9539

Fish antifreeze protein F006 / 9539
Fish antifreeze protein. Molecular model of a fish antifreeze protein (AFP) from the winter flounder (Pseudopleuronectes americanus)

Background imageAlpha Helix Collection: Bacteriophage ATPase molecule F006 / 9536

Bacteriophage ATPase molecule F006 / 9536
Bacteriophage ATPase. Molecular model of an ATP synthase (ATPase) molecule from the phi 12 bacteriophage. ATPase is an important enzyme that provides energy for cells through the synthesis of

Background imageAlpha Helix Collection: Molecular motor protein F006 / 9537

Molecular motor protein F006 / 9537
Molecular motor protein. Molecular model of a two-headed motor protein, Myosin V. Motor proteins convert chemical energy into mechanical movements in response to specific chemical stimuli

Background imageAlpha Helix Collection: Cytochrome b6f complex, molecular model F006 / 9533

Cytochrome b6f complex, molecular model F006 / 9533
Cytochrome b6f complex, molecular model. Cytochrome molecules perform oxidation and reduction reactions for electron transport

Background imageAlpha Helix Collection: Glycosylation enzyme molecule F006 / 9535

Glycosylation enzyme molecule F006 / 9535
Glycosylation enzyme. Molecular model of the enzyme N-acetylglucosamine (GlcNAc) transferase. This intracellular enzyme adds N-acetylglucosamine molecules to target proteins

Background imageAlpha Helix Collection: TATA box-binding protein complex F006 / 9534

TATA box-binding protein complex F006 / 9534
TATA box-binding protein complex. Molecular model showing a yeast TATA box-binding protein (TBP) complexed with a strand of DNA (deoxyribonucleic acid, red and blue) and transcription factor IIB

Background imageAlpha Helix Collection: Transcription factor and ribosomal RNA F006 / 9530

Transcription factor and ribosomal RNA F006 / 9530
Transcription factor and ribosomal RNA (rRNA). Molecular model showing the 6 zinc fingers of transcription factor IIIA (yellow) bound to RNA (ribonucleic acid)

Background imageAlpha Helix Collection: Bacteriophage restriction enzyme F006 / 9531

Bacteriophage restriction enzyme F006 / 9531
Bacteriophage restriction enzyme. Molecular model of the restriction enzyme endonuclease V (yellow) from the bacteriophage T4 complexed with DNA (deoxyribonucleic acid, red and blue)

Background imageAlpha Helix Collection: Squalene-hopene cyclase molecule F006 / 9529

Squalene-hopene cyclase molecule F006 / 9529
Squalene-hopene cyclase, molecular model. This bacterial enzyme catalyses the cyclization of squalene to hopene

Background imageAlpha Helix Collection: Self-splicing RNA intron, molecular model F006 / 9527

Self-splicing RNA intron, molecular model F006 / 9527
Self-splicing RNA intron, molecular model. Splicing is the process where a non-coding fragment (intron) of a strand of nucleic acid (DNA, deoxyribonucleic acid; or RNA, ribonucleic acid) is removed

Background imageAlpha Helix Collection: Ubiquitin molecule F006 / 9528

Ubiquitin molecule F006 / 9528
Ubiquitin, molecular model. Ubiquitin is found in all eukaryotic cells. When a protein is damaged or old it will be tagged by several ubiquitin molecules

Background imageAlpha Helix Collection: Cobra venom molecule F006 / 9524

Cobra venom molecule F006 / 9524
Cobra venom. Molecular model of toxin b, a long neurotoxin from a king cobra (Ophiophagus hannah)

Background imageAlpha Helix Collection: Tumour suppressor protein with DNA F006 / 9523

Tumour suppressor protein with DNA F006 / 9523
Tumour suppressor protein. Molecular model of the tumour suppressor protein p53 (beige) bound to a molecule of DNA (deoxyribonucleic acid, red and blue)

Background imageAlpha Helix Collection: Tarantula toxin molecule F006 / 9525

Tarantula toxin molecule F006 / 9525
Tarantula toxin. Molecular model of a peptide toxin from the tarantula Grammostola spatulata. This toxin works by inhibiting mechanosensitive ion channels

Background imageAlpha Helix Collection: Nitric oxide synthase molecule F006 / 9521

Nitric oxide synthase molecule F006 / 9521
Nitric oxide synthase, molecular model. This enzyme catalyses the production of nitric oxide from L-arginine. Nitric oxide is involved in cellular signalling

Background imageAlpha Helix Collection: LAC repressor molecule F006 / 9520

LAC repressor molecule F006 / 9520
LAC repressor. Molecular model of a LAC (lactose) repressor molecule. The LAC repressor inhibits the expression of genes that code for an enzyme which metabolizes lactose in bacteria

Background imageAlpha Helix Collection: SV40 virus capsid, molecular model F006 / 9508

SV40 virus capsid, molecular model F006 / 9508
SV40 virus capsid, molecular model. Simian virus 40 (SV40) is found in monkeys such as Rhesus monkeys and macaques. Potentially tumour-causing, it is used in laboratory research and in vaccines

Background imageAlpha Helix Collection: Carbonic anhydrase molecule F006 / 9518

Carbonic anhydrase molecule F006 / 9518
Carbonic anhydrase, molecular model. This enzyme catalyses the reversible hydration of carbon dioxide

Background imageAlpha Helix Collection: Reverse transcriptase and inhibitor F006 / 9519

Reverse transcriptase and inhibitor F006 / 9519
Reverse transcriptase and inhibitor. Molecular model of HIV reverse transcriptase complexed with a non-nucleoside reverse transcriptase inhibitor drug

Background imageAlpha Helix Collection: Transducin protein beta-gamma complex F006 / 9514

Transducin protein beta-gamma complex F006 / 9514
Transducin protein beta-gamma complex. Molecular model of the beta-gamma dimer of the heterotrimeric G protein transducin

Background imageAlpha Helix Collection: Trypsinogen molecule with inhibitor F006 / 9517

Trypsinogen molecule with inhibitor F006 / 9517
Trypsinogen molecule. Molecular model of trypsinogen, the precursor to the digestive protease enzyme trypsin, complexed with an inhibitor

Background imageAlpha Helix Collection: Transcription factor and ribosomal RNA F006 / 9516

Transcription factor and ribosomal RNA F006 / 9516
Transcription factor and ribosomal RNA (rRNA). Molecular model showing the 6 zinc fingers of transcription factor IIIA (yellow) bound to RNA (ribonucleic acid)

Background imageAlpha Helix Collection: T cell receptor, molecular model F006 / 9515

T cell receptor, molecular model F006 / 9515
T cell receptor. Molecular model of an alpha T cell receptor. T cell receptors are protein complexes found on the surface of a type of white blood cell called T lymphocytes (or T cells)

Background imageAlpha Helix Collection: DNA polymerase with DNA F006 / 9512

DNA polymerase with DNA F006 / 9512
DNA polymerase with DNA. Molecular model of DNA polymerase (purple) complexed with a molecule of DNA (deoxyribonucleic acid, pink and blue)

Background imageAlpha Helix Collection: DNA helicase molecule F006 / 9509

DNA helicase molecule F006 / 9509
DNA helicase. Molecular model of a helicase molecule from the SV40 virus. Helicases are enzymes that separate the two strands of the DNA double helix

Background imageAlpha Helix Collection: Simian virus SV40 large T antigen F006 / 9513

Simian virus SV40 large T antigen F006 / 9513
Simian virus (SV40) large T antigen, molecular model. This antigen is from the simian vacuolating virus 40 (SV40). Large T antigens play a role in regulating the viral life cycle of

Background imageAlpha Helix Collection: Transcription activation of IFN-beta gene F006 / 9510

Transcription activation of IFN-beta gene F006 / 9510
Transcription activation of IFN-beta gene. Molecular model of an enhanceosome containing the transcription factors IRF-3, ATF-2 and c-Jun bound to the interferon-beta (IFN-beta)

Background imageAlpha Helix Collection: Type IV collagen, molecular model F006 / 9511

Type IV collagen, molecular model F006 / 9511
Type IV collagen, molecular model. Collagen is a long structural protein, formed from amino acids that make up polypeptide strands that twist around each other

Background imageAlpha Helix Collection: Calcium ATPase ion pump F006 / 9507

Calcium ATPase ion pump F006 / 9507
Calcium ATPase ion pump, molecular model. This enzyme is found in muscle cell membranes, where it pumps calcium in and out of muscle cells and controls muscle contractions

Background imageAlpha Helix Collection: Scavenger mRNA-decapping enzyme F006 / 9505

Scavenger mRNA-decapping enzyme F006 / 9505
Scavenger mRNA-decapping enzyme, molecular model. This enzyme hydrolyses the cap that is left after 3 to 5 mRNA degradation

Background imageAlpha Helix Collection: Parvovirus particle, molecular model F006 / 9499

Parvovirus particle, molecular model F006 / 9499
Parvovirus particle. Molecular model showing the structure of the capsid (outer protein coat) of a human parvovirus (family Parvoviridae) particle

Background imageAlpha Helix Collection: Staphylococcal enterotoxin C2 molecule F006 / 9506

Staphylococcal enterotoxin C2 molecule F006 / 9506
Staphylococcal enterotoxin C2. Molecular model of the C2 enterotoxin from the bacterium Staphylococcus aureus

Background imageAlpha Helix Collection: Aquaporin membrane protein F006 / 9503

Aquaporin membrane protein F006 / 9503
Aquaporin membrane protein, molecular model. Aquaporins are membrane proteins that form channels (lower right) that help water molecules pass in and out of cells

Background imageAlpha Helix Collection: Yeast enzyme, molecular model F006 / 9498

Yeast enzyme, molecular model F006 / 9498
Yeast enzyme. Molecular model of an enzyme from bakers yeast (Saccharomyces cerevisiae). This is the 20S proteasome. A proteasome is a complex type of proteinase (protein-digesting enzyme)

Background imageAlpha Helix Collection: SARS virus capsid protein F006 / 9504

SARS virus capsid protein F006 / 9504
SARS virus capsid protein, molecular model. This protein is responsible for binding the capsid (outer coat) of the SARS (severe acute respiratory syndrome)

Background imageAlpha Helix Collection: RNA-induced silencing complex F006 / 9502

RNA-induced silencing complex F006 / 9502
RNA-induced silencing complex (RISC), molecular model. This complex consists of a bacterial argonaute protein bound to a small interfering RNA (siRNA) molecule (red and blue)

Background imageAlpha Helix Collection: Photosystem II molecule F006 / 9500

Photosystem II molecule F006 / 9500
Photosystem II. Molecular model of the photosystem II complex. Photosystems are protein complexes involved in photosynthesis

Background imageAlpha Helix Collection: Photosystem II molecule F006 / 9497

Photosystem II molecule F006 / 9497
Photosystem II. Molecular model of the photosystem II complex. Photosystems are protein complexes involved in photosynthesis

Background imageAlpha Helix Collection: Nerve growth factor bound to receptor F006 / 9501

Nerve growth factor bound to receptor F006 / 9501
Nerve growth factor bound to receptor. Molecular model of nerve growth factor (NGF) bound to the p75 neurotrophin receptor. NGF is a neurotrophin that acts on the development and function of nerves

Background imageAlpha Helix Collection: Rhinovirus capsid, molecular model F006 / 9490

Rhinovirus capsid, molecular model F006 / 9490
Rhinovirus capsid, molecular model. This is human rhinovirus. The rhinovirus infects the upper respiratory tract and is the cause of the common cold. It is spread by coughs and sneezes

Background imageAlpha Helix Collection: H1 antigen from 1918 influenza virus F006 / 9495

H1 antigen from 1918 influenza virus F006 / 9495
H1 antigen from 1918 influenza virus

Background imageAlpha Helix Collection: HIV reverse transcription enzyme F006 / 9494

HIV reverse transcription enzyme F006 / 9494
HIV reverse transcription enzyme. Molecular model of the reverse transcriptase enzyme (blue and green) found in HIV (the human immunodeficiency virus)

Background imageAlpha Helix Collection: EcoRV restriction enzyme molecule F006 / 9496

EcoRV restriction enzyme molecule F006 / 9496
EcoRV restriction enzyme. Molecular model of the type II restriction enzyme EcoRV (pink and yellow) bound to a cleaved section of DNA (deoxyribonucleic acid, red and blue)



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The alpha helix, a fundamental structure in biology, plays a crucial role in various molecular processes. From DNA transcription to protein synthesis, this intricate arrangement is found throughout the biological world. In the realm of genetics, the alpha helix participates in DNA transcription by aiding in the unwinding and separation of strands. Its elegant spiral shape allows for efficient reading and copying of genetic information. When it comes to proteins, the alpha helix serves as a secondary structure that contributes to their stability and function. Visualized through stunning artwork or molecular models, its coiled form adds strength and flexibility to these vital biomolecules. One example where we can observe this remarkable structure is within the nucleosome molecule. Here, DNA wraps around histone proteins forming tight coils resembling beads on a string – with each bead representing an alpha helix. Another instance occurs within bacterial ribosomes responsible for protein synthesis. The presence of multiple alpha helices enables precise positioning of molecules during translation – ensuring accurate assembly of amino acids into functional proteins. Viruses also exploit this structural motif; one such case being HIV reverse transcription enzyme. This enzyme utilizes an alpha helical region to convert viral RNA into DNA – a critical step in viral replication. Similarly, hepatitis C virus enzyme employs an intricate network of alpha helices depicted by molecular models. These structures aid in catalyzing chemical reactions necessary for viral survival and proliferation. Moving beyond viruses, manganese superoxide dismutase enzyme showcases how nature harnesses the power of the alpha helix for antioxidant defense mechanisms within cells. Its tightly wound coils protect against harmful free radicals that can damage cellular components. Alpha-helical motifs are not limited to enzymes alone but extend to larger molecules like human serum albumin or Argonaute protein involved in gene regulation pathways. Their well-defined arrangements contribute significantly to their respective functions within our bodies' complex systems.